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Archive ouverte | Le Grégam, Loïc | CCSD

International audience. The goal of isotope-based fluxomics approaches is to quantify metabolic fluxes in living organisms. 13C-fluxomics provides a detailed phenotypic description of the actual metabolic state of s...

IsoDesign: substrate design for isotopic labelling experiments

Archive ouverte | Le Grégam, Loïc | CCSD

International audience. In systems biology, studying the functioning of the intricate network of biochemical reactions governing cellular metabolism is crucial for elucidating the behaviour of living organisms. Meta...

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Archive ouverte | Le Grégam, Loïc | CCSD

International audience. Abstract Summary Quantification of growth parameters and extracellular uptake and production fluxes is central in systems and synthetic biology. Fluxes can be estimated using various mathemat...

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