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Lung transplantation as a rescue option in childhood critical pulmonary Langerhans cell histiocytosis

Archive ouverte | Heritier, Sébastien | CCSD

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Archive ouverte | Thalhammer, Julian | CCSD

International audience. Hematological involvement (HI) is one of the life-threatening risk organs (ROs) in Langerhans cell histiocytosis (LCH). Lahey criteria have defined HI since 1975 as hemoglobin <10 ...

BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy

Archive ouverte | Heritier, Sébastien | CCSD

International audience. PURPOSE:Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia with a broad spectrum of clinical manifestations and outcomes in children. The somatic BRAF(V600E) mutation oc...

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