Shifting the limits in wheat research and breeding using a fully annotated reference genome

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Appels, Rudi | Eversole, Kellye | Stein, Nils | Feuillet, Catherine | Keller, Beat | Rogers, Jane | Pozniak, Curtis | Choulet, Frédéric | Distelfeld, Assaf | Poland, Jesse | Ronen, Gil | Sharpe, Andrew | Barad, Omer | Baruch, Kobi | Keeble-Gagnère, Gabriel | Mascher, Martin | Ben-Zvi, Gil | Josselin, Ambre-Aurore | Himmelbach, Axel | Balfourier, François | Gutierrez-Gonzalez, Juan | Hayden, Matthew | Koh, Chushin | Muehlbauer, Gary | Pasam, Raj | Paux, Etienne | Rigault, Philippe | Tibbits, Josquin | Tiwari, Vijay | Spannagl, Manuel | Lang, Daniel | Gundlach, Heidrun | Haberer, Georg | Mayer, Klaus | Ormanbekova, Danara | Prade, Verena | Šimková, Hana | Wicker, Thomas | Swarbreck, David | Rimbert, Hélène | Felder, Marius | Guilhot, Nicolas | Kaithakottil, Gemy | Keilwagen, Jens | Leroy, Philippe | Lux, Thomas | Twardziok, Sven | Venturini, Luca | Juhász, Angéla | Abrouk, Michael | Fischer, Iris | Uauy, Cristobal | Borrill, Philippa | Ramirez-Gonzalez, Ricardo | Arnaud, Dominique | Chalabi, Smahane | Chalhoub, Boulos | Cory, Aron | Datla, Raju | Davey, Mark | Jacobs, John | Robinson, Stephen | Steuernagel, Burkhard | van Ex, Fred | Wulff, Brande | Benhamed, Moussa | Bendahmane, Abdelhafid | Concia, Lorenzo | Latrasse, David | Bartoš, Jan | Bellec, Arnaud | Berges, Hélène | Doležel, Jaroslav | Frenkel, Zeev | Gill, Bikram | Korol, Abraham | Letellier, Thomas | Olsen, Odd-Arne | Singh, Kuldeep | Valárik, Miroslav | van der Vossen, Edwin | Vautrin, Sonia | Weining, Song | Fahima, Tzion | Glikson, Vladimir | Raats, Dina | Číhalíková, Jarmila | Toegelová, Helena | Vrána, Jan | Sourdille, Pierre | Darrier, Benoit | Barabaschi, Delfina | Cattivelli, Luigi | Hernandez, Pilar | Galvez, Sergio | Budak, Hikmet | Jones, Jonathan | Witek, Kamil | Yu, Guotai | Small, Ian | Melonek, Joanna | Zhou, Ruonan | Belova, Tatiana | Kanyuka, Kostya | King, Robert | Nilsen, Kirby | Walkowiak, Sean | Cuthbert, Richard | Knox, Ron | Wiebe, Krysta | Xiang, Daoquan | Rohde, Antje | Golds, Timothy | Čížková, Jana | Akpinar, Bala Ani | Biyiklioglu, Sezgi | Gao, Liangliang | N’daiye, Amidou | Kubaláková, Marie | Šafář, Jan | Alfama, Françoise | Adam-Blondon, Anne-Françoise | Flores, Raphael | Guerche, Claire | Loaec, Mikaël | Quesneville, Hadi | Condie, Janet | Ens, Jennifer | Maclachlan, Ron | Tan, Yifang | Alberti, Adriana | Aury, Jean-Marc | Barbe, Valérie | Couloux, Arnaud | Cruaud, Corinne | Labadie, Karine | Mangenot, Sophie | Wincker, Patrick | Kaur, Gaganpreet | Luo, Mingcheng | Sehgal, Sunish | Chhuneja, Parveen | Gupta, Om Prakash | Jindal, Suruchi | Kaur, Parampreet | Malik, Palvi | Sharma, Priti | Yadav, Bharat | Singh, Nagendra | Khurana, Jitendra | Chaudhary, Chanderkant | Khurana, Paramjit | Kumar, Vinod | Mahato, Ajay | Mathur, Saloni | Sevanthi, Amitha | Sharma, Naveen | Tomar, Ram Sewak | Holušová, Kateřina | Plíhal, Ondřej | Clark, Matthew | Heavens, Darren | Kettleborough, George | Wright, Jon | Balcárková, Barbora | Hu, Yuqin | Salina, Elena | Ravin, Nikolai | Skryabin, Konstantin | Beletsky, Alexey | Kadnikov, Vitaly | Mardanov, Andrey | Nesterov, Michail | Rakitin, Andrey | Sergeeva, Ekaterina | Handa, Hirokazu | Kanamori, Hiroyuki | Katagiri, Satoshi | Kobayashi, Fuminori | Nasuda, Shuhei | Tanaka, Tsuyoshi | Wu, Jianzhong | Cattonaro, Federica | Jiumeng, Min | Kugler, Karl | Pfeifer, Matthias | Sandve, Simen | Xun, Xu | Zhan, Bujie | Batley, Jacqueline | Bayer, Philipp | Edwards, David | Hayashi, Satomi | Tulpová, Zuzana | Visendi, Paul | Cui, Licao | Du, Xianghong | Feng, Kewei | Nie, Xiaojun | Tong, Wei | Wang, Le

Edité par CCSD ; American Association for the Advancement of Science (AAAS) -

International audience. Insights from the annotated wheat genome Wheat is one of the major sources of food for much of the world. However, because bread wheat's genome is a large hybrid mix of three separate subgenomes, it has been difficult to produce a high-quality reference sequence. Using recent advances in sequencing, the International Wheat Genome Sequencing Consortium presents an annotated reference genome with a detailed analysis of gene content among subgenomes and the structural organization for all the chromosomes. Examples of quantitative trait mapping and CRISPR-based genome modification show the potential for using this genome in agricultural research and breeding. Ramírez-González et al. exploited the fruits of this endeavor to identify tissue-specific biased gene expression and coexpression networks during development and exposure to stress. These resources will accelerate our understanding of the genetic basis of bread wheat. Science , this issue p. eaar7191 ; see also p. eaar6089

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