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Archive ouverte | Bonnefont, Jérôme | CCSD

International audience. The mechanism of action of acetaminophen is currently widely discussed. Direct inhibition of cyclooxygenase isoforms remains the commonly advanced hypothesis. We combined behavioral studies w...

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Archive ouverte | Barrière, David, A | CCSD

International audience. The discovery that paracetamol is metabolized to the potent TRPV1 activator N-(4-hydroxyphenyl)-5Z,8Z,11Z,14Zeicosatetraenamide (AM404) and that this metabolite contributes to paracetamol's a...

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Archive ouverte | Daulhac, Laurence | CCSD

International audience

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