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99m Tc-NTP 15-5 Imaging for Cartilage Involvement in Experimental Rheumatoid Arthritis: Comparison with Routinely Used Molecular Imaging Methods and Sensitivity to Chronic Nonsteroidal Antiinflammatory Drug Treatment

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Khairnar, Amit | Marchand, Fabien | Vidal, Aurélien | Etienne, Monique | Miladi, Imen | Auzeloux, Philippe | Cachin, Florent | Eschalier, Alain | Chezal, Jean-Michel | Ardid, Denis | Miot-Noirault, Elisabeth

Edité par CCSD ; Society of Nuclear Medicine -

International audience. This study determined, using the intraarticular complete Freund adjuvant arthritis mice model, whether the radiotracer (99m)Tc-N-(triethylammonium)-3-propyl-[15]ane-N5 ((99m)Tc-NTP 15-5) targeting proteoglycans has a pathophysiologic validity for in vivo imaging of rheumatoid arthritis (RA) and its response to chronic nonsteroidal antiinflammatory drugs.

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