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An integrative analysis using iCLIP-seq and RNA-Seq to identify genes post-transcriptionally regulated by the cataract-linked RNA-binding protein CELF1 in the lens

Archive ouverte | Duot, Matthieu | CCSD

International audience

Identification of alternative spliced RNA targets of the cataract-linked RNA-binding protein CELF1: use of an multi-omics approach based an iCLIP-seq and RNA-seq

Archive ouverte | Duot, Matthieu | CCSD

International audience

High-Throughput Transcriptomics of Celf1 Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology

Archive ouverte | Siddam, Archana D. | CCSD

International audience. Defects in the development of the ocular lens can cause congenital cataracts. To understand the various etiologies of congenital cataracts, it is important to characterize the genes linked to...

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