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A mechanosensitive caveolae–invadosome interplay drives matrix remodelling for cancer cell invasion

Archive ouverte | Monteiro, Pedro | CCSD

International audience. Invadosomes and caveolae are mechanosensitive structures that are implicated in metastasis. Here, we describe a unique juxtaposition of caveola clusters and matrix degradative invadosomes at ...

Codependencies of mTORC1 signaling and endolysosomal actin structures

Archive ouverte | Priya, Amulya | CCSD

International audience. The mechanistic target of rapamycin complex 1 (mTORC1) is part of the amino acid sensing machinery that becomes activated on the endolysosomal surface in response to nutrient cues. Branched a...

A mechanosensitive caveolae–invadosome interplay drives matrix remodelling for cancer cell invasion

Archive ouverte | Monteiro, Pedro | CCSD

International audience. Abstract Invadosomes and caveolae are mechanosensitive structures that are implicated in metastasis. Here, we describe a unique juxtaposition of caveola clusters and matrix degradative invado...

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