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RNA-seq data for detecting reliable SNPs & genotypes in livestock species: interest for coding variant characterization and cis-regulation analysis by allele-specific expression !

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Jehl, Frédéric | Degalez, Fabien | Bernard, Maria | Lecerf, Frédéric | Lagoutte, Laetitia | Desert, Colette | Coulée, Manon | Bouchez, Olivier | Leroux, Sophie | Abasht, Behnam | Tixier-Boichard, Michèle | Bed’hom, Bertrand | Burlot, Thierry | Gourichon, David | Acloque, Hervé | Foissac, Sylvain | Djebali, Sarah | Giuffra, Elisabetta | Zerjal, Tatiana | Pitel, Frédérique | Klopp, Christophe | Lagarrigue, Sandrine

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International audience. Context 2 • For detecting polymorphisms in the whole genome of a population, DNA-seq data analyzed by the bioinformatics GATK tool is the standard approach. • DNA-seq data are expensive to generate and to store, because these data are large

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