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Insights into Hox protein function from a large scale combinatorial analysis of protein domains.

Archive ouverte | Merabet, Samir | CCSD

International audience. Protein function is encoded within protein sequence and protein domains. However, how protein domains cooperate within a protein to modulate overall activity and how this impacts functional d...

Selection of distinct Hox–Extradenticle interaction modes fine-tunes Hox protein activity

Archive ouverte | Saadaoui, Mehdi | CCSD

International audience. Hox genes encode transcription factors widely used for diversifying animal body plans in development and evolution. To achieve functional specificity, Hox proteins associate with PBC class pr...

Selection of distinct Hox-Extradenticle interaction modes fine-tunes Hox protein activity.

Archive ouverte | Saadaoui, Mehdi | CCSD

International audience. Hox genes encode transcription factors widely used for diversifying animal body plans in development and evolution. To achieve functional specificity, Hox proteins associate with PBC class pr...

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