A numerical prediction of fiber orientation in hydrogels for extrusion-based 3D printing

Archive ouverte

Mai, van Than | Rieger, Romain | Chatelin, Robin | Courtial, Edwin-Joffrey | Boulocher, Caroline

Edité par CCSD -

International audience. The purpose of this study is to develop a numerical strategy able to compute and predict the flow-induced orientation of the fibers within an hydrogel during extrusion-based 3D printing process. The probability distribution function approach was used to describe the orientation of a fiber population. This approach was coupled to a computational fluid dynamic (CFD) method to compute the fluid flow which transports the fibers. Numerical computations were performed for a planar channel and a conical nozzle geometry. The results showed that the fiber orientation during the extrusion process is delayed by the hydrogel rheological behavior while the final fiber orientation remains the same. This study presents the first analysis for the fiber orientation prediction in hydrogel for extrusion-base 3D printing.

Suggestions

Du même auteur

Contactless mechanical stimulation of tissue engineered constructs: Development and validation of an air-pulse device

Archive ouverte | Marchal-Chaud, Hugo | CCSD

3. International audience. Objective : Tissue engineering (TE) is the study and development of biological substitutes to restore, maintain or improve tissue function. Tissue engineered constructs (TECs) still presen...

Numerical modeling of hydrogel scaffold anisotropy during extrusion-based 3D printing for tissue engineering

Archive ouverte | Mai, V. T. | CCSD

Extrusion-based 3D printing is a widely utilized tool in tissue engineering, offering precise 3D control of bioinks to construct organ-sized biomaterial objects with hierarchically organized cellularized scaffolds. The internal or...

Structural anisotropy characterization of fiber-reinforced hydrogels scaffolds during extrusion-based 3D printing for soft tissue repair.

Archive ouverte | Morcos, Anatole | CCSD

Engineered biomimicking soft tissues have been greatly improved by the use of extrusion-based 3D bioprinting techniques. They are classically made of fiberreinforced hydrogels with designed rheological behavior in order to give me...

Chargement des enrichissements...