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Archive ouverte | Lagarrigue, Sylviane | CCSD

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Archive ouverte | Giroit, Albert | CCSD

Objective: Aberrant hepatic glucose production contributes to the development of hyperglycemia and is a hallmark of type 2 diabetes. In a recent study, we showed that the transcription factor E2F1, a component of the cell cycle ma...

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Archive ouverte | Lai, Qiuwen | CCSD

International audience. Cholesterol accumulation in the liver is an early event in nonalcoholic fatty liver disease (NAFLD). Here, we demonstrate that E2F1 plays a crucial role in maintaining cellular cholesterol ho...

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