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A refined picture of the native amine dehydrogenase family revealed by extensive biodiversity screening

Archive ouverte | Elisée, Eddy | CCSD

International audience. Native amine dehydrogenases offer sustainable access to chiral amines, so the search for scaffolds capable of converting more diverse carbonyl compounds is required to reach the full potentia...

MODAMDH: identification of diverse Amine Dehydrogenases by screening biodiversity using sequence and structure-based approaches

Archive ouverte | Eddy, Elisée | CCSD

International audience. The current boom in environmental genomics data provides a huge resource of new sequences of potential biocatalysts. Through the MODAMDH project, we focus on one of the key biocatalysts named...

A family of native amine dehydrogenases for the asymmetric reductive amination of ketones

Archive ouverte | Mayol, Ombeline | CCSD

International audience. The asymmetric reductive amination of ketones enables the one-step synthesis of chiral amines from readily available starting materials. Here we report the discovery of a family of native NAD...

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