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Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks

Archive ouverte | Perea-Gomez, Aitana | CCSD

International audience. The anterior visceral endoderm plays a pivotal role in establishing anterior-posterior polarity of the mouse embryo, but the molecular nature of the signals required remains to be determined....

HNF3 β and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo

Archive ouverte | Perea-Gómez, Aitana | CCSD

International audience. Abstract Recent embryological and genetic experiments have suggested that the anterior visceral endoderm and the anterior primitive streak of the early mouse gastrula function as head- and tr...

Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification

Archive ouverte | Rhinn, Muriel | CCSD

International audience. The homeobox gene Otx2 is a mouse cognate of the Drosophila orthodenticle gene, which is required for development of the brain, rostral to rhombomere three. We have investigated the mechanism...

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