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Human Three-dimensional engineered neural tissue reveals cellular and molecularevents following cytomegalovirus infection

Archive ouverte | Cosset, Érika | CCSD

International audience. Human cytomegalovirus (HCMV) is the most common cause of congenital infection of the central nervous system (CNS). To overcome the limited access to human neural tissue and stringent species ...

The relationship between brain tumor cell invasion of engineered neural tissues and in vivo features of glioblastoma.

Archive ouverte | Nayernia, Zeynab | CCSD

International audience. Glioblastoma is an aggressive brain tumor characterized by its high propensity for local invasion, formation of secondary foci within the brain, as well as areas of necrosis. This study aims ...

Identification of a miRNA multi-targeting therapeutic strategy in glioblastoma

Archive ouverte | Bassot, Arthur | CCSD

International audience. Glioblastoma (GBM) is a deadly and the most common primary brain tumor in adults. Due to their regulation of a high number of mRNA transcripts, microRNAs (miRNAs) are key molecules in the con...

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