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Defects of the body plan of mutant embryos lacking Lim1, Otx2 or Hnf3beta activity.

Archive ouverte | Kinder, Simon J. | CCSD

International audience. The orientation of the anterior-posterior (A-P) axis was examined in gastrula-stage Hnf3beta, Otx2 and Lim1 null mutant embryos that display defective axis development. In situ hybridization ...

β-Catenin is essential for Müllerian duct regression during male sexual differentiation.

Archive ouverte | Kobayashi, Akio | CCSD

International audience. During male sexual differentiation, the transforming growth factor-β (TGF-β) signaling molecule anti-Müllerian hormone (AMH; also known as Müllerian inhibiting substance, MIS) is secreted by ...

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