Engineered Synthetic STxB for Enhanced Cytosolic Delivery

Archive ouverte | Hadjerci, Justine | CCSD

International audience. Many molecular targets for cancer therapy are located in the cytosol. Therapeutic macromolecules are generally not able to spontaneously translocate across membranes to reach these cytosolic ...

Variants STxB synthétiques

Archive ouverte | Johannes, Ludger | CCSD

A synthetic delivery vector for mucosal vaccination

Archive ouverte | Billet, Anne | CCSD

International audience. The success of mRNA-based vaccines during the Covid-19 pandemic has highlighted the value of this new platform for vaccine development against infectious disease. However, the CD8+ T cell res...