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Physical basis of some membrane shaping mechanisms

Archive ouverte | Simunovic, Mijo | CCSD

International audience. In vesicular transport pathways, membrane proteins and lipids are internalized, externalized or transported within cells, not by bulk diffusion of single molecules, but embedded in the membra...

Comparing physical mechanisms for membrane curvature-driven sorting of BAR-domain proteins

Archive ouverte | Tsai, Feng-Ching | CCSD

International audience. Protein enrichment at specific membrane locations in cells is crucial for many cellular functions. It is well-recognized that the ability of some proteins to sense membrane curvature contribu...

Friction Mediates Scission of Tubular Membranes Scaffolded by BAR Proteins

Archive ouverte | Simunovic, Mijo | CCSD

International audience. Membrane scission is essential for intracellular trafficking. While BAR domain proteins such as endophilin have been reported in dynamin-independent scission of tubular membrane necks, the cu...

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