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Neuron-glia interactions: May 24S-hydroxycholesterol be a signal molecule in the retina in the course of retinal ganglion cell loss?

Archive ouverte | Fourgeux, Cynthia | CCSD

International audience. Purpose: Cholesterol 24S-hydroxylase (CYP46A1) is an enzyme which converts cholesterol into 24S-hydroxycholesterol (24SOH). CYP46A1 is expressed in retinal ganglion cells (RGC) and in activat...

Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model

Archive ouverte | Viau, Sabrina | CCSD

International audience. Background This study was conducted to evaluate the efficacy of dietary n-6 and n-3 polyunsaturated fatty acids (PUFAs) in dry eye in a rat model.Methods Female Lewis rats were fed with diets...

No consequence of dietary omega-3 polyunsaturated fatty acid deficiency on the severity of scopolamine-induced dry eye

Archive ouverte | Viau, Sabrina | CCSD

International audience. Purpose:Epidemiological studies suggest that dietary omega-3 polyunsaturated fatty acids (PUFAs) may protect against prevalence of dry eye. This work aimed to evaluate whether a dietary defic...

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