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Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvature

Archive ouverte | Sternberg, Jenna | CCSD

International audience. Defects in cerebrospinal fluid (CSF) flow may contribute to idiopathic scoliosis. However, the mechanisms underlying detection of CSF flow in the central canal of the spinal cord are unknown....

Sensory neurons contacting the cerebrospinal fluid require the Reissner fiber to detect spinal curvature in vivo

Archive ouverte | Orts-Del'Immagine, Adeline | CCSD

International audience

Origin and role of the cerebrospinal fluid bidirectional flow in the central canal

Archive ouverte | Thouvenin, Olivier | CCSD

International audience. Circulation of the cerebrospinal fluid (CSF) contributes to body axis formation and brain development. Here, we investigated the unexplained origins of the CSF flow bidirectionality in the ce...

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