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Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy

Archive ouverte | Gayi, Elinam | CCSD

X-linked myotubular myopathy (XLMTM, also known as XLCNM) is a severe congenital muscular disorder due to mutations in the myotubularin gene, MTM1. It is characterized by generalized hypotonia, leading to neonatal death of most pa...

A Hypothesized Therapeutic Role of (Z)-Endoxifen in Duchenne Muscular Dystrophy (DMD)

Archive ouverte | Remmel, H Lawrence | CCSD

International audience

Platelets Facilitate the Wound-Healing Capability of Mesenchymal Stem Cells by Mitochondrial Transfer and Metabolic Reprogramming

Archive ouverte | Levoux, Jennyfer | CCSD

International audience. Platelets are known to enhance the wound-healing activity of mesenchymal stem cells (MSCs). However, the mechanism by which platelets improve the therapeutic potential of MSCs has not been el...

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