Deciphering pathological remodelling of the human cartilage extracellular matrix in osteoarthritis at the supramolecular level

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Deciphering pathological remodelling of the human cartilage extracellular matrix in osteoarthritis at the supramolecular level

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Edité par CCSD ; Royal Society of Chemistry -

International audience. Osteoarthritis induces a combination of chemical, structural and nanomechanical changes to collagen fibrils and aggrecan aggregates, the main building blocks of cartilage ECM, that may be mimicked by specific enzymatic reactions.

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