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Galectin-3 Binding to α 5 β 1 Integrin in Pore Suspended Biomembranes

Archive ouverte | Sarangi, Nirod Kumar | CCSD

International audience. Galectin-3 (Gal3) is a β-galactoside binding lectin that mediates many physiological functions, including the binding of cells to the extracellular matrix for which the glycoprotein 51 inte...

Spatial N-glycan rearrangement on α 5 β 1 integrin nucleates galectin-3 oligomers to determine endocytic fate

Archive ouverte | Shafaq-Zadah, Massiullah | CCSD

Summary Membrane glycoproteins frequently adopt different conformations when altering between active and inactive states. Here, we discover a molecular switch that exploits dynamic spatial rearrangements of N-glycans during such c...

Quantitative Methods to Study Endocytosis and Retrograde Transport of Cargo Proteins

Archive ouverte | Shafaq-Zadah, Massiullah | CCSD

International audience

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