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Number needed to treat with ursodeoxycholic acid therapy to prevent liver transplantation or death in primary biliary cholangitis

Archive ouverte | Harms, Maren, H | CCSD

International audience. Objective: The clinical benefit of ursodeoxycholic acid (UDCA) in primary biliary cholangitis (PBC) has never been reported in absolute measures. The aim of this study was to assess the numbe...

A placebo-controlled randomised trial of budesonide for PBC following an insufficient response to UDCA

Archive ouverte | Hirschfield, Gideon, M | CCSD

International audience. Placebo + 12-16 mg/kg UDCA N = 22 9 mg Budesonide + 12-16 mg/kg UDCA N = 40

Performance of non-invasive tests and histology for the prediction of clinical outcomes in patients with non-alcoholic fatty liver disease: an individual participant data meta-analysis

Archive ouverte | Mózes, Ferenc | CCSD

International audience. Background: Histologically assessed liver fibrosis stage has prognostic significance in patients with non-alcoholic fatty liver disease (NAFLD) and is accepted as a surrogate endpoint in clin...

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