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Suppressor Mutations in LptF Bypass Essentiality of LptC by Forming a Six-Protein Transenvelope Bridge That Efficiently Transports Lipopolysaccharide

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Falchi, Federica | Taylor, Rebecca | Rowe, Sebastian | Moura, Elisabete | Baeta, Tiago | Laguri, Cedric | Simorre, Jean-Pierre | Kahne, Daniel | Polissi, Alessandra | Sperandeo, Paola

Edité par CCSD ; American Society for Microbiology -

International audience. The presence of an external LPS layer in the outer membrane makes Gram-negative bacteria intrinsically resistant to many antibiotics. Millions of LPS molecules are transported to the cell surface per generation by the Lpt molecular machine made, in E. coli , by seven essential proteins.

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International audience. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the def...

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