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Macroautophagy in lymphatic endothelial cells inhibits T cell–mediated autoimmunity

Archive ouverte | Harlé, Guillaume | CCSD

International audience. Lymphatic endothelial cells (LECs) present peripheral tissue antigens to induce T cell tolerance. In addition, LECs are the main source of sphingosine-1-phosphate (S1P), promoting naive T cel...

Absence of MHC-II expression by lymph node stromal cells results in autoimmunity

Archive ouverte | Dubrot, Juan | CCSD

International audience. How lymph node stromal cells (LNSCs) shape peripheral T-cell responses remains unclear. We have previously demonstrated that murine LNSCs, lymphatic endothelial cells (LECs), blood endothelia...

Macroautophagy in lymphatic endothelial cells inhibits T cell–mediated autoimmunity

Archive ouverte | Harlé, Guillaume | CCSD

International audience. Lymphatic endothelial cells (LECs) present peripheral tissue antigens to induce T cell tolerance. In addition, LECs are the main source of sphingosine-1-phosphate (S1P), promoting naive T cel...

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