Therapeutical modulation of plasmacytoid dendritic cells in experimental arthritis

Archive ouverte | Nehmar, Ramzi | CCSD

OBJECTIVES: The role of plasmacytoid dendritic cells (pDCs) and type I Interferons in rheumatoid arthritis (RA) remains controversial. To explore their contribution to RA pathogenesis, we induced experimental arthritis in various ...

A mouse model of MSU-induced acute inflammation in vivo suggests imiquimod-dependent targeting of Il-1 beta as relevant therapy for gout patients

Archive ouverte | Mariotte, Alexandre | CCSD

NLRP3- and AIM2-autonomy in a mouse model of MSU crystal-induced acute inflammation in vivo highlights imiquimod-dependent targeting of Il-1E expression as relevant therapy for gout patients.

Archive ouverte | Mariotte, Alexandre | CCSD

L'article est publié dans la revue sous le titre définitif :"A mouse model of MSU-induced acute inflammation in vivo suggests imiquimod-dependent targeting of Il-1β as relevant therapy for gout patients". International audience. ...