The tubulin code: Empowering microtubules

Archive ouverte

Magiera, Maria, M

Edité par CCSD ; Elsevier -

International audience. Microtubules are essential filamentous components of the cytoskeleton that are present in virtually all eukaryotic cells, where they ensure essential functions: Microtubules establish and maintain cell shape, serve as tracks for the intracellular transport, or build the mitotic and meiotic spindles that segregate genetic material during cell division. Microtubules further form the structural backbone of cilia and flagella, essential organelles that are involved in cell-cell signalling and cell motility.

Suggestions

Du même auteur

Mechanisms and functions of the tubulin code 1 2 3 4

Archive ouverte | Janke, Carsten | CCSD

International audience

Tubulin polyglutamylation, a regulator of microtubule functions, can cause neurodegeneration

Archive ouverte | Bodakuntla, Satish | CCSD

International audience. Neurodegenerative diseases lead to a progressive demise of neuronal functions that ultimately results in neuronal death. Besides a large variety of molecular pathways that have been linked to...

Purification of Tubulin with Controlled Posttranslational Modifications and Isotypes from Limited Sources by Polymerization-Depolymerization Cycles

Archive ouverte | Bodakuntla, Satish | CCSD

International audience. One important aspect of studies of the microtubule cytoskeleton is the investigation of microtubule behavior in in vitro reconstitution experiments. They allow the analysis of the intrinsic p...

Chargement des enrichissements...