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CD49d is a disease progression biomarker and a potential target for immunotherapy in Duchenne muscular dystrophy

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International audience. Background: Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene. The immune inflammatory response also contributes to disease progression in DMD patients. In a pre...

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International audience. In the translational process of developing innovative therapies for DMD (Duchenne muscular dystrophy), the last preclinical validation step is often carried out in the most relevant animal mo...

Crosstalk Between Innate and T Cell Adaptive Immunity With(in) the Muscle

Archive ouverte | Bonomo, Adriana, C. | CCSD

International audience. Growing evidence demonstrates a continuous interaction between the immune system and the skeletal muscle in inflammatory diseases of different pathogenetic origins, in dystrophic conditions s...

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