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Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium

Archive ouverte | Jenny, Marjorie | CCSD

Endocrine cells of the pancreas and the gastrointestinal tract derive from multipotent endodermal stem cells. We have shown previously that the basic helix- loop-helix (bHLH) transcription factor neurogenin3 (ngn3) is required for...

The Microenvironment Controls CDX2 Homeobox Gene Expression in Colorectal Cancer Cells

Archive ouverte | Benahmed, Fairouz | CCSD

International audience. The homeobox gene CDX2 plays a major role in development, especially in the gut, and it also acts as a tumor suppressor in the adult colon. Using orthotopic and heterotopic xenografts of huma...

Multiple Regulatory Regions Control the Complex Expression Pattern of the Mouse Cdx2 Homeobox Gene

Archive ouverte | Benahmed, Fairouz | CCSD

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