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Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes

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Theis, Kevin | Dheilly, Nolwenn | Klassen, Jonathan | Brucker, Robert | Baines, John | Bosch, Thomas | Cryan, John | Gilbert, Scott | Goodnight, Charles | Lloyd, Elisabeth | Sapp, Jan | Vandenkoornhuyse, Philippe | Zilber-Rosenberg, Ilana | Rosenberg, Eugene | Bordenstein, Seth

Edité par CCSD -

International audience. Given the complexity of host-microbiota symbioses, scientists and philosophers are asking questions at new biological levels of hierarchical organization—what is a holobiont and hologenome? When should this vocabulary be applied? Are these concepts a null hypothesis for host-microbe systems or limited to a certain spectrum of symbiotic interactions such as host-microbial coevolution? Critical discourse is necessary in this nascent area, but productive discourse requires that skeptics and proponents use the same lexicon.

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