Suggestions

Du même auteur

Modulators of hERAP2 discovered by High-Throughput Screening

Archive ouverte | Medve, Laura | CCSD

International audience. Endoplasmic reticulum aminopeptidase 2, ERAP2, is an emerging pharmacological target in cancer immunotherapy and control of autoinflammatory diseases, as it is involved in antigen processing....

Discovery of New Nanomolar Selective IRAP Inhibitors

Archive ouverte | He, Ben | CCSD

International audience. Among the M1 family of oxytocinase aminopeptidases, insulin-regulated aminopeptidase IRAP, is an emerging drug target implicated in various biological pathways and particularly in MHC-I antig...

Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening

Archive ouverte | Leroux, Florence | CCSD

International audience. Insulin-degrading enzyme, IDE, is a metalloprotease implicated in the metabolism of key peptides such as insulin, glucagon, β-amyloid peptide. Recent studies have pointed out its broader role...

Chargement des enrichissements...