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Adrenal GIPR expression and chromosome 19q13 microduplications in GIP-dependent Cushing’s syndrome

Archive ouverte | Lecoq, Anne | CCSD

International audience. GIP-dependent Cushing's syndrome is caused by ectopic expression of glucose-dependent insulinotropic polypeptide receptor (GIPR) in cortisol-producing adrenal adenomas or in bilateral macrono...

KDM1A genotyping and expression in 146 sporadic somatotroph pituitary adenomas

Archive ouverte | Chasseloup, Fanny | CCSD

International audience. Abstract Importance A paradoxical increase of growth hormone (GH) following oral glucose load has been described in ∼30% of patients with acromegaly and has been related to the ectopic expres...

Hypermethylator Phenotype and Ectopic GIP Receptor in GNAS Mutation-Negative Somatotropinomas

Archive ouverte | Hage, Mirella | CCSD

International audience. Abstract Context Besides GNAS gene mutations, the molecular pathogenesis of somatotroph adenomas responsible for gigantism and acromegaly remains elusive. Objective To investigate alternative...

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