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SARS-CoV-2 and neurological disorders: the revelance of biomarkers?

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Bigot-Corbel, Edith | Lanore, Aymeric | Raulet, Celia | Delorme, Cécile | Azulay, Jean-Philippe | Lehmann, Sylvain | Beaudeux, Jean-Louis | Beauvieux, Marie-Christine | Sapin, Vincent | Peoc'H, Katell | Rucheton, Benoit | Kamel, Saïd

Edité par CCSD ; John Libbey Eurotext -

International audience. Soon after the pandemic, numerous publications described cases of neurological disorders associated with the SARS-CoV-2 infection. The range of neurological symptoms is becoming increasingly more extensive as the pandemic progresses. However, it is not yet well established whether the manifestations are due to direct viral damage to the nervous system or indirect consequences of the infection. This review presents an inventory of the biochemical markers studied in the context of neurological disorders related to SARS-CoV-2. By reflecting various physiopathological mechanisms, these biomarkers allow both a better understanding of the pathophysiology of Covid-19 and a contribution to the diagnosis of neurologic troubles; they could participate in the prognostic evaluation of patients.

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