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Urinary Leukotriene E 4 and Prostaglandin D 2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study

Archive ouverte | Kolmert, Johan | CCSD

International audience

Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study

Archive ouverte | Reinke, Stacey | CCSD

International audience. Introduction Asthma is a heterogeneous disease with poorly defined phenotypes. Severe asthmatics often receive multiple treatments including oral corticosteroids (OCS). Treatment may modify t...

Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation

Archive ouverte | Sparreman Mikus, Maria | CCSD

International audience. Rationale Asthma phenotyping requires novel biomarker discovery. Objectives To identify plasma biomarkers associated with asthma phenotypes by application of a new proteomic panel to samples ...

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