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Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells

Archive ouverte | Kind, Jop | CCSD

International audience. Mammalian interphase chromosomes interact with the nuclear lamina (NL) through hundreds of large lamina-associated domains (LADs). We report a method to map NL contacts genome-wide in single ...

Single-Cell Dynamics of Genome-Nuclear Lamina Interactions

Archive ouverte | Kind, Jop | CCSD

International audience. The nuclear lamina (NL) interacts with hundreds of large genomic regions termed lamina associated domains (LADs). The dynamics of these interactions and the relation to epigenetic modificatio...

Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis

Archive ouverte | Jarvis, Joseph | CCSD

International audience. Background: Cryptococcal meningitis is a leading cause of human immunodeficiency virus (HIV)-related death in sub-Saharan Africa. Whether a treatment regimen that includes a single high dose ...

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