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Enlarged endosomes are believed to be the first morphological change observed in Alzheimer's disease brains (AD). They are found in sporadic cases with no pathological evidence of AD yet, in Down syndrome (DS) as early as 28 weeks...

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Archive ouverte | Panchal, Maï | CCSD

International audience

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Archive ouverte | Traboulsi, Tatiana | CCSD

International audience. The field of stem cell-based embryo-like models is rapidly evolving, providing in vitro models of in utero stages of mammalian development. Here, we detail steps to first establish adherent s...

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