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Mild Therapeutic Hypothermia Protects from Acute and Chronic Renal Ischemia-Reperfusion Injury in Mice by Mitigated Mitochondrial Dysfunction and Modulation of Local and Systemic Inflammation

Archive ouverte | Schleef, Maxime | CCSD

International audience. Renal ischemia-reperfusion (IR) injury can lead to acute kidney injury, increasing the risk of developing chronic kidney disease. We hypothesized that mild therapeutic hypothermia (mTH), 34 °...

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Archive ouverte | Lemoine, Sandrine | CCSD

International audience. BackgroundThere is experimental evidence that lethal ischemia-reperfusion injury (IRI) is largely due to mitochondrial permeability transition pore (mPTP) opening, which can be prevented by c...

Dose and timing of injections for effective cyclosporine A pretreatment before renal ischemia reperfusion in mice

Archive ouverte | Lemoine, Sandrine | CCSD

International audience

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