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GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation

Archive ouverte | Drareni, Karima | CCSD

International audience. Hypertrophic white adipose tissue (WAT) represents a maladaptive mechanism linked to the risk for developing type 2 diabetes in humans. However, the molecular events that predispose WAT to hy...

Monocytopenia, monocyte morphological anomalies and hyperinflammation characterise severe COVID ‐19 in type 2 diabetes

Archive ouverte | Alzaid, Fawaz | CCSD

International audience. Early in the COVID-19 pandemic, type 2 diabetes (T2D) was marked as a risk factor for severe disease and mortality. Inflammation is central to the aetiology of both conditions where variation...

Blood Monocyte Phenotype Is A Marker of Cardiovascular Risk in Type 2 Diabetes

Archive ouverte | Julla, Jean-Baptiste | CCSD

International audience. BACKGROUND: Diabetes is a major risk factor for atherosclerotic cardiovascular diseases with a 2-fold higher risk of cardiovascular events in people with diabetes compared with those without....

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