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Simple randomization did not protect against bias in smaller trials

Archive ouverte | Nguyen, Tri-Long | CCSD

International audience. OBJECTIVES:By removing systematic differences across treatment groups, simple randomization is assumed to protect against bias. However, random differences may remain if the sample size is in...

Comparison of the ability of double-robust estimators to correct bias in propensity score matching analysis. A Monte Carlo simulation study

Archive ouverte | Nguyen, Tri-Long | CCSD

International audience. OBJECTIVE:As covariates are not always adequately balanced after propensity score matching and double- adjustment can be used to remove residual confounding, we compared the performance of se...

Double-adjustment in propensity score matching analysis: choosing a threshold for considering residual imbalance

Archive ouverte | Nguyen, Tri-Long | CCSD

International audience. BACKGROUND:Double-adjustment can be used to remove confounding if imbalance exists after propensity score (PS) matching. However, it is not always possible to include all covariates in adjust...

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