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Tannin extract from maritime pine bark exhibits anticancer properties by targeting the epigenetic UHRF1/DNMT1 tandem leading to the re-expression of TP73

Archive ouverte | Ashraf, Waseem | CCSD

International audience. Maritime pine bark is a rich source of polyphenolic compounds and is commonly employed as a herbal supplement worldwide.

Targeting microRNA/UHRF1 pathways as a novel strategy for cancer therapy (Review)

Archive ouverte | Bronner, Christian | CCSD

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Thymoquinone challenges UHRF1 to commit auto-ubiquitination: a key event for apoptosis induction in cancer cells

Archive ouverte | Ibrahim, Abdulkhaleg | CCSD

Down-regulation of UHRF1 (Ubiquitin-like containing PHD and Ring Finger 1) in Jurkat cells, induced by natural anticancer compounds such as thymoquinone, allows re-expression of tumor suppressor genes such as p73 and p16 INK4A. In...

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