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Le poumon est sensible aux effets locaux et à distance des microbiotes

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Mathieu, Elliot | Marquant, Quentin | Descamps, Delphyne | Riffault, Sabine | Saint-Criq, Vinciane | Thomas, Muriel

Edité par CCSD -

International audience. The respiratory physiology is influenced by flows of microorganisms originating mainly from the bucconasal sphere but also by bacterial signals produced locally in the lung and remotely by the intestinal microbiota. This review describes the composition, establishment and functions of the lung microbiota as well as the relationships between the intestinal and pulmonary microbiota underlying the intestine–lung axis. . La physiologie respiratoire est influencée par des flux de micro-organismes provenant principalement de la sphère bucco-nasale mais aussi par des signaux bactériens produits localement dans le poumon et à distance par le microbiote intestinal. Cette revue décrit la composition, la mise en place et les fonctions du microbiote du poumon ainsi que les relations entre le microbiote intestinal et le microbiote pulmonaire déterminant l’axe intestin–poumon.

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