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Fibroblast growth factor 19 stimulates water intake

Archive ouverte | Ursic-Bedoya, José | CCSD

International audience. Fibroblast growth factor 19 (FGF19) is a hormone with pleiotropic metabolic functions, leading to ongoing development of analogues for treatment of metabolic disorders. On the other hand, FGF...

FGF19 and its analog Aldafermin cooperate with MYC to induce aggressive hepatocarcinogenesis

Archive ouverte | Ursic-Bedoya, José | CCSD

International audience. FGF19 hormone has pleiotropic metabolic functions, including the modulation of insulin sensitivity, glucose/lipid metabolism and energy homeostasis. On top of its physiological metabolic role...

GOLT1B Activation in Hepatitis C Virus-Infected Hepatocytes Links ER Trafficking and Viral Replication

Archive ouverte | Butterworth, Jacqueline | CCSD

International audience. Chronic hepatitis C carries a high risk of development of hepatocellular carcinoma (HCC), trig-gered by both direct and indirect effects of the virus. We examined cell-autonomous alterations ...

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