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Rituximab is an effective treatment in patients with pemphigus vulgaris and demonstrates a steroid‐sparing effect

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Chen, D, M | Odueyungbo, A | Csinady, E | Gearhart, L | Lehane, P | Cheu, M | Maho‐vaillant, M | Prost‐squarcioni, C | Hebert, V | Houivet, E | Calbo, S | Caillot, F | Golinski, M, L | Labeille, B | Picard‐dahan, C | Paul, C | Richard, M, A | Bouaziz, J, D | Duvert‐lehembre, S | Bernard, P | Caux, F | Alexandre, M | Ingen‐housz‐oro, S | Vabres, P | Delaporte, E | Quereux, G | Dupuy, A | Debarbieux, S | Avenel‐audran, M | d'Incan, M | Bedane, C | Bénéton, N | Jullien, D | Dupin, N | Misery, L | Machet, L | Beylot‐barry, M | Dereure, O | Sassolas, B | Benichou, J | Musette, P | Joly, P

Edité par CCSD ; Wiley -

International audience. Background Corticosteroids (CS) with or without adjuvant immunosuppressant agents are standard treatment for pemphigus vulgaris (PV). The efficacy of adjuvant therapies in minimizing steroid-related adverse events (AEs) is unproven. Objectives To utilize data collected in a French investigator-initiated, phase III, open-label, randomized controlled trial to demonstrate the efficacy and safety of rituximab and seek approval for its use in PV.

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