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Peripheral natural killer cells in chronic hepatitis B patients display multiple molecular features of T cell exhaustion

Archive ouverte | Marotel, Marie | CCSD

International audience. Antiviral effectors such as natural killer (NK) cells have impaired functions in chronic hepatitis B (CHB) patients. The molecular mechanism responsible for this dysfunction remains poorly ch...

One-Year Follow-Up of Natural Killer Cell Activity in Multiple Myeloma Patients Treated With Adjuvant Lenalidomide Therapy

Archive ouverte | Besson, Laurie | CCSD

International audience. Multiple myeloma (MM) is a proliferation of tumoral plasma B cells that is still incurable. Natural killer (NK) cells can recognize and kill MM cells in vitro and can limit MM growth in vivo....

Alteration of Natural Killer cell phenotype and function in obese individuals

Archive ouverte | Viel, Sébastien | CCSD

International audience. Obesity is associated with increased cancer rates and higher susceptibility to infections. The adipose tissue of obese individuals is inflammatory and may negatively impact on innate and adap...

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