High Power Electromagnetic Waves Exposure of Healthy and Tumor Bearing Mice: Assessment of Effects on Mice Growth, Behavior, Tumor Growth and Vessel Permeabilization

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Kolosnjaj-Tabi, Jelena | Golzio, Muriel | Bellard, Elisabeth | Catrain, Alexandre | Chretiennot, Thomas | Saurin, Quentin | Tarayre, Jacques | Vezinet, René | Rols, Marie-Pierre

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International audience. High power radiofrequencies may transiently or permanently disrupt the functioning of electronic devices, but their effect on living systems remains unknown. Herein we thus evaluated certain biological effects upon narrowband and wide band high-power electromagnetic (HPEM) waves' exposure of healthy and tumor-bearing mice. In field experiments, the exposure to 1.5 GHz narrowband electromagnetic fields with the incident amplitude peak value level in the range of 40 kV/m, and 150 MHz wide band electric fields with the amplitude peak value in the range of 200 kV/m, did not induce any significant alterations of animal or tumor growth. While we did not observe any behavioral changes in mice during the application of narrowband signals, when wide-band HPEM signals were applied, mice could behave in a similar way as they respond to loud noise signals. Moreover, the effect of wide band signals was assessed on blood vessels per-20 meability in real time in dorsal-chamber-bearing mice, exposed using wide band signal applica-21 tors. Our pilot study conducted within the applicator and performed at the laboratory scale, sug-22 gests that the exposure to wide band signals with the amplitude of 47.5 kV/m does not result in 23 increased vessel permeability.

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