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DDE Transposon as Public Goods. Les transposons DDE en tant que bien public

Archive ouverte | Tsakou-Ngouafo, Louis | CCSD

International audience. DDE Transposons have been recruited at least four times as site-specific recombination activating gene allowing programmed DNA elimination in eukaryotes. The described cases are RAG in jawed ...

The piggyBac-derived protein 5 (PGBD5) transposes both the closely and the distantly related piggyBac-like elements Tcr-pble and Ifp2

Archive ouverte | Helou, Laura | CCSD

International audience. The vertebrate piggyBac derived transposase 5 (PGBD5) encodes a domesticated transposase, which is active and able to transpose its distantly related piggyBac-like element (pble), Ifp2. This ...

Identification of RAG-like transposons in protostomes suggests their ancient bilaterian origin

Archive ouverte | Martin, Eliza, C | CCSD

International audience. Background: V(D) J recombination is essential for adaptive immunity in jawed vertebrates and is initiated by the RAG1-RAG2 endonuclease. The RAG1 and RAG2 genes are thought to have evolved fr...

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