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SARS-CoV-2 variants of concern are associated with lower RT-PCR amplification cycles between January and March 2021 in France

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Roquebert, Benedicte | Haim-Boukobza, Stéphanie | Trombert-Paolantoni, Sabine | Lecorche, Emmanuel | Verdurme, Laura | Foulongne, Vincent | Burrel, Sonia | Alizon, Samuel | Sofonea, Mircea, T

Edité par CCSD ; Elsevier -

International audience. SARS-CoV-2 variants raise concern regarding the mortality caused by COVID-19 epidemics. We analyse 88,375 cycle amplication (Ct) values from variant-specic RT-PCR tests performed between January 26 and March 13, 2021. We estimate that on March 12, nearly 85% of the infections were caused by the Alpha variant and that its transmission advantage over wild type strains was between 38 and 44%. We also nd that tests positive for Alpha and Beta/Gamma variants exhibit signicantly lower cycle threshold (Ct) values.

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