Specific detection of memory T-cells in COVID-19 patients using standardized whole-blood Interferon gammarelease assay. Letter to the editor

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Mouton, William | Compagnon, Christelle | Saker, Kahina | Daniel, Soizic | Djelabi, Sophia | Lacoux, Xavier | Pozzetto, Bruno | Oriol, Guy | Laubreton, Daphné | Prieux, Margaux | Fassier, Jean-Baptiste | Guibert, Nicolas | Massardier-Pilonchery, Amélie | Alfaiate, Dulce | Berthier, Franck | Walzer, Thierry | Marvel, Jacqueline | Brengel-Pesce, Karen | Trouiller-Assant, Sophie

Edité par CCSD -

Antigen-specific T-cells are essential for protective immunity against SARS-CoV-2. We set up a semi-automated whole-blood Interferon-gamma release assay (WB IGRA) to monitor the T-cell response after stimulation with SARS-CoV-2 peptide pools. We report that the WB IGRA is complementary to serological assays to assess SARS-CoV-2 immunity.

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