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Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascade

Archive ouverte | Leyva-Castillo, Juan Manuel | CCSD

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Counterregulation between thymic stromal lymphopoietin– and IL-23–driven immune axes shapes skin inflammation in mice with epidermal barrier defects

Archive ouverte | Li, Jiagui | CCSD

International audience. Background: Epidermal barrier dysfunction has been recognized as a critical factor in the initiation and exacerbation of skin inflammation, particularly in patients with atopic dermatitis (AD...

RORalpha-expressing T regulatory cells restrain allergic skin inflammation

Archive ouverte | Malhotra, Nidhi | CCSD

Atopic dermatitis is an allergic inflammatory skin disease characterized by the production of the type 2 cytokines in the skin by type 2 innate lymphoid cells (ILC2s) and T helper 2 (TH2) cells, and tissue eosinophilia. Using two ...

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