The Paris-Sud yeast structural genomics pilot-project: from structure to function

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The Paris-Sud yeast structural genomics pilot-project: from structure to function

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Edité par CCSD ; Elsevier -

International audience. We present here the outlines and results from our yeast structural genomics (YSG) pilot-project. A lab-scale platform for the systematic production and structure determination is presented. In order to validate this approach, 250 non-membrane proteins of unknown structure were targeted. Strategies and final statistics are evaluated. We finally discuss the opportunity of structural genomics programs to contribute to functional biochemical annotation.

Langue: en

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